The Uppsala Study of Adult Men (ULSAM) is a longitudinal study based on all available 50-year-old men in Uppsala, Sweden, born between 19. ![]() High lipoprotein (a) levels may be a stronger risk factor for silent myocardial infarction (MI) compared to clinically recognized MI. Risk factors for major Q/QS patterns need not be the same as traditional risk factors for clinically recognized CHD. T wave abnormalities on resting ECG should be given special attention and correlated with clinical information. T wave abnormalities and high fasting glucose levels were significant independent predictors for the development of ST segment depression without abnormal Q/QS pattern. T wave abnormalities (Odds ratio 3.11, 95% CI 1.18–8.17), high lipoprotein (a) levels, high body mass index (BMI) and smoking were identified as significant independent predictors for the development of abnormal major Q/QS patterns. ResultsĪt the age of 70, 9% had developed a major abnormal Q/QS pattern, but 63% of these subjects had not been previously hospitalized due to MI, while 57% with symptomatic MI between age 50 and 70 had no major Q/QS pattern at age 70. Anthropometrical and metabolic factors, ECG abnormalities and vital signs from a health survey of men at age 50 were related to ECG abnormalities identified in the same cohort 20 years later. Predictors for development of different ECG abnormalities were identified in a population-based study using stepwise logistic regression. Our aim was to identify factors that could predict the development of ECG markers of CHD, such as abnormal Q/QS patterns, ST segment depression and T wave abnormalities, in 70-year-old men, irrespective of clinical outcome. ![]() Most studies on risk factors for development of coronary heart disease (CHD) have been based on the clinical outcome of CHD.
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